High Prevalence ofblaCTX-MExtended Spectrum Beta-Lactamase Genes inKlebsiella pneumoniaeIsolates from a Tertiary Care Hospital: First report ofblaSHV-12,blaSHV-31,blaSHV-38, andblaCTX-M-15in Brazil

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High prevalence of bla(CTX-M) extended spectrum beta-lactamase genes in Klebsiella pneumoniae isolates from a tertiary care hospital: first report of bla(SHV-12), bla(SHV-31), bla(SHV-38), and bla(CTX-M-15) in Brazil.

The aim of this study was to investigate the presence and prevalence of bla(TEM), bla(SHV), and bla(CTX-M) and bla(GES)-like genes, responsible for extended spectrum beta-lactamases (ESBLs) production in clinical isolates of Klebsiella pneumoniae collected from a Brazilian tertiary care hospital. Sixty-five ESBL producing K. pneumoniae isolates, collected between 2005 and 2007, were screened by...

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BACKGROUND Extended-spectrum beta (beta)-lactamase (ESBL)-producing enterobacteria are major emerging pathogens in nosocomial infections. METHODOLOGY The combination disk synergy test was used to evaluate 202 consecutive non-repeated Klebsiella pneumoniae (K. pneumonia) strains for ESBL production. The strains were isolated from various clinical specimens of hospitalized patients over the per...

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High Prevalence of CTXM-15 Type Extended-Spectrum Beta-Lactamase Among Clinical Isolates of Klebsiella Pneumoniae

Background: Production of β–lactamases by enterobacteriacea, especially Klebsiella pneumoniae, is one of the emerging health problems in the world. The purpose of this study was to assess the frequency of blaCTX-M15 gene in K. pneumoniae isolates and determine the molecular diversity of CTXM producing isolates. Methods: In...

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CTX-M group of extended spectrum beta lactamases (ESBLs) represents a rapidly emerging problem in many countries. The prevalence of nosocomial bla CTX-M-1 producing Enterobacteriaceae strains has not been reported earlier in Indian hospitals. This study describes molecular subtyping of nosocomial bla CTX-M producing strains of Enterobacteriaceae . Polymerase chain reaction with primers specific...

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ژورنال

عنوان ژورنال: Microbial Drug Resistance

سال: 2011

ISSN: 1076-6294,1931-8448

DOI: 10.1089/mdr.2010.0055